LC-MS Targeted (TMIC-Prime)

$65.00$85.00

LC-MS Targeted (TMIC-Prime) metabolomic analysis is useful for plasma, serum urine, tissue, milk, CSF, soil, water, meat, fruits, vegetables, feces, cell media, cell lysate, and cells.

Description

Matrices / Biosamples:  Plasma, Serum, Urine, Tissue, Milk, CSF, Meat, Fruits, Vegetables, Feces, Cell Media, Cell Lysate, Cells

Volume Requirement:  80 ul; 30-40 mg

Pathways: TCA Cycle, Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Lipid metabolism, Urea Cycle, Redox Balance, 1-Carbon metabolism

Compound Classes:  Lipids, Fatty Acids, Amino Acids, Organic acids, Biogenic amines, Acylcarnitines, Phosphatidylcholines, LysoPCs, Sphingomyelins, Sugars, Neurotransmitters

Cost per Sample:  Academic/Government $65; Industry $85

Number of Compounds:  143

Quantitative:  Absolute

Compound List:  Acetylornithine, Asymmetric dimethylarginine, Total dimethylarginine, alpha-Aminoadipicacid, Carnosine, Carnosine, Creatinine, Dopa, Dopamine, Histamine, Kynurenine, Methioninesulfoxide, Hydroxyproline (t4-OH-Pro), Hydroxyproline (c4-OH-Pro), Phenylethylamine, Putrescine, Sarcosine, Serotonin, Spermidine, Spermine, Diacetylspermine, Taurine, Tyramine, Nitrotyrosine, Alanine, Arginine, Asparagine, Aspartate, Citrulline, Glutamate, Glutamine, Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Proline, Serine, Threonine, Tryptophan, Tyrosine, Valine, Betaine, TMAO, Choline, Creatine, Phosphocreatine, Methylhistidine, Homocysteine, C0 (Carnitine), C2 (Acetylcarnitine), C3:1 (Propenoylcarnitine), C3 (Propionylcarnitine), C4:1 (Butenylcarnitine), C4 (butyrylcarnitine), C3-OH (hydroxyPropionylcarnitine), C5:1 (Tiglylcarnitine), C5 (Valerylcarnitine), C4-OH (C3-DC) (Hydroxybutyrylcarnitine), C6:1 (Hexenoylcarnitine), C6 (C4:1-DC) (Hexanoylcarnitine), C5-OH (C3-DC-M), C5:1-DC (Glutaconylcarnitine) (hydroxyvalerylcarnitine), C5-DC (C6-OH)(Glutarylcarnitine), C8 (Octanoylcarnitine), C5-M-DC (methylglutarylcarnitine), C9 (Nonaylcarnitine), C7-DC (pimelylcarnitine), C10:2 (decadienylcarnitine), C10:1 (Decenoylcarnitine), C10 (Decanoylcarnitine), C12:1 (Dodecenoylcarnitine), C12 (dodecanoylcarnitine), C14:2 (Tetradecadienylcarnitine), C14:1 (tetradecenoyl carnitine), C14 (tetradecanoylcarnitine), C12-DC (dodecanedioylcarnitine), C14:2-OH (hydroxytetradecadienylcarnitine), C14:1-OH (Hydroxytetradecenoyl carnitine), C16:2 (Hexadecadienylcarnitine), C16:1 (Hexadecenoylcarnitine), C16 (Hexadecanoylcarnitine), C16:2-OH (hydroxyhexadecadienylcarnitine), C16:1-OH (Hydroxyhexadecenoylcarnitine), C16-OH (hydroxyhexadecanoylcarnitine), C18:2 (Octadecadienylcarnitine), C18:1 (Octadecenoylcarnitine), C18:1 (Octadecenoylcarnitine), C18 (Octadecanoylcarnitine), C18:1-OH (Hydroxyoctadecenoylcarnitine), Glucose, PC diacyl (aa) C36:6, PC aa C32:2, PC aa C38:0, PC aa C38:6, PC aa C40:1, PC aa C40:2, PC aa C40:6, PC acyl-alkyl (ae) C40:6, PC ae C36:0 , lysophophatidylcholine (lysoPC a C18:2), SM (OH) C14:1, SM (OH) C16:1, SM (OH) C22:1, SM (OH) C22:2, SM (OH) C24:1, SM C16:0, SM C16:1, SM C18:0, SM C18:1, SM C20:2, lysoPC a C14:0, lysoPC a C16:0, lysoPC a C16:1, lysoPC a C17:0, lysoPC a C18:0, lysoPC a C18:1, lysoPC a C18:2, lysoPC a C20:3, lysoPC a C20:4, lysoPC a C24:0, lysoPC a C26:0, lysoPC a C26:1, lysoPC a C28:0, lysoPC a C28:1, Lactic acid, beta-Hydroxybutyric acid, alpha-Ketoglutaric acid, Citric acid, Butyric acid , Propionic acid, HPHPA, para-hydroxyhippuric acid, Succinic acid, Fumaric acid, Pyruvic acid, Isobutyric acid, Hippuric acid, Methylmalonic acid, Homovanillic acid, Indole acetic acid, Uric acid


Species:
  Humans, Crop Plants, Medicinal Plants, Mice, Rats, Livestock, Fish, Yeast, E. coli, Water, Soil, Raw Foods (Meat, Fruits, Vegetables), Prepared Foods

Validation or Publication:  PMID: 30706502; Minerbi, A.; Gonzalez, E.; Brereton, N. J. B.; Anjarkouchian, A.; Dewar, K.; Fitzcharles, M. A.; Chevalier, S.; Shir, Y. Altered microbiome composition in individuals with fibromyalgia. Pain 2019, 160, 2589-2602. Anal. Chem. 2020, 92, 15, 10627–10634;
Magan, J. B.; O’Callaghan, T. F.; Zheng, J.; Zhang, L.; Mandal, R.; Hennessy, D.; Fenelon, M. A.; Wishart, D. S.; Kelly, A. L.; McCarthy, N. A. Impact of bovine diet on metabolomic profile of skim milk and whey protein ingredients. Metabolites 2019, 9, 10.3390/metabo9120305. Metabolites 2020, 10, 233; doi:10.3390/metabo10060233

Additional information

Client Classification

Industry, Government, Academic