LC-MS Targeted (Biocrates p400)


LC-MS Targeted (Biocrates p400) metabolomic analysis is useful for plasma, serum urine, tissue, milk, CSF, meat, cell media, cell lysate, and cells.


Matrices / Biosamples:  Plasma, Serum, Urine, Tissue, Milk, CSF, Meat, Cell Media, Cell Lysate, Cells

Volume Requirement:  20 ul; 30-40 mg

Pathways: Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Lipid metabolism, Urea Cycle. Redox Balance, Cholesterol metabolism, Micorbial metabolism

Compound Classes:  Lipids, Fatty Acids, Amino Acids, Organic acids, Biogenic amines, Acylcarnitines, Phosphatidylcholines, LysoPCs, Sphingomyelins, Sugars, Neurotransmitters

Cost per Sample:  Academic/Government $135; Industry $180

Number of Compounds:  Up to 408

Quantitative:  Absolute

Compound List:  Acetylornithine, Asymmetric Dimethylarginine, Symmetric Dimethylarginine, Total Dimethylarginine, alpha-Aminoadipicacid, Carnosine, Creatinine, Dopa, Dopamine, Histamine, Kynurenine, Methioninesulfoxide, Nitrotyrosine, Hydroxyproline,Putrescine,  Phenylethylamine, Sarcosine, Serotonin, Spermidine, Spermine, Taurine, Alanine, Arginine, Asparagine, Aspartate, Citrulline, Glutamate, Glutamine, Glycine, Histidine, Isoleucine, Leucine, Lysine, Methionine, Ornithine, Phenylalanine, Serine,  Proline, Threonine, Tryptophan, Tyrosine, Valine, Hexoses, Carnitine, Acetylcarnitine, Propionylcarnitine, Malonylcarnitine, Hydroxypropionylcarnitine, Propenoylcarnitine, Butyrylcarnitine, Methylmalonylcarnitine, Hydroxybutyrylcarnitine, Butenylcarnitine, Fumarylcarnitine, Valerylcarnitine, Glutarylcarnitine, Hydroxyvalerylcarnitine, Tiglylcarnitine, Glutaconylcarnitine, Hexanoylcarnitine, Adipoylcarnitine, Hydroxyhexanoylcarnitine, Hexenoylcarnitine, Heptanoylcarnitine, Pimeloylcarnitine, Octanoylcarnitine,  Nonaylcarnitine,  Hydroxyoctenoylcarnitine,  Octenoylcarnitine, Decanoylcarnitine AC10:0 AC10:1, Decadienoylcarnitine, Decatrienoylcarnitine, Dimethylnonanoylcarnitine, Dodecanoylcarnitine, Dodecanedioylcarnitine, Dodecenoylcarnitine, Tridecanoylcarnitine, Tetradecanoylcarnitine, Hydroxymyristoylcarnitine, Tetradecenoylcarnitine, Carboxytridecenoylcarnitine, Hydroxytetradecenoylcarnitine, Tetradecadienoylcarnitine, Hydroxytetradecadienoylcarnitine, Pentadecanoylcarnitine, Hexadecanoylcarnitine, Hexadecenoylcarnitine,  Hydroxyhexadecanoylcarnitine, Hydroxyhexadecenoylcarnitine, Hexadecadienoylcarnitine, Hydroxyhexadecadienoylcarnitine, Heptadecanoylcarnitine, Octadecanoylcarnitine AC(18:0) AC(18:1), Hydroxyoctadecenoylcarnitine, Octadecadienylcarnitine, Nonadecanoylcarnitine, Diglyceride DG(32:2) DG(32:2) DG(34:1) DG(345:3) DG(36:3) DG(36:4) DG(38:0) DG(39:0) DG(41:1) DG(42:0) DG(42:1) DG(42:2) DG(44:3) DG-O(32:2) DG-O(34:1) DG-O(36:4), Triglyceride TG(44:1) TG(44:2) TG(44:4) TG(45:2) TG(48:1) TG(48:3) TG(49:1 TG(49:2) TG(50:1) TG(50:2) TG(50:3) TG(50:4) TG(51:1) TG(51:2) TG(51:3) TG(51:4) TG(51:5) TG(52:2) TG(52:3) TG(52:4) TG(52:5) TG(52:6) TG(52:7) TG(53:3) TG(53:4) TG(53:5) TG(53:6) TG(54:2) TG(54:3) TG(54:4) TG(54:5) TG(54:6) TG(54:7) TG(55:6) TG(55:7) TG(55:8) TG(55:9) TG(56:6 TG(56:7) TG(56:8) TG(56:9), Lysophosphatidylcholine LPC(12:0) LPC(14:0) LPC(15:0) LPC(16:0) LPC(16:1) LPC(17:0) LPC(17:1) LPC(18:0) LPC(18:1) LPC(18:2) LPC(20:0) LPC(20:1) LPC(20:2) LPC(20:3) LPC(20:4) LPC(22:5) LPC(22:6) LPC(24:1) LPC-O(16:1) LPC-O(17:1) LPC-O(18:0) LPC-O(18:1) LPC-O(18:2), Phosphatidylcholine PC(24:0) PC(25:0) PC(26:0) PC(27:0) PC(27:1) PC(28:1) PC(29:0) PC(29:1) PC(29:2) PC(30:0) PC(30:1) PC(30:2) PC(30:3) PC(31:0) PC(31:1) PC(31:2) PC(31:3) PC(32:0) PC(32:1) PC(32:2) PC(32:3) PC(32:4) PC(32:5) PC(32:6) PC(33:0PC) PC(33:1) PC(33:2) PC(33:3) PC(33:4) PC(33:50 PC(33:6) PC(34:0) PC(34:1) PC(34:2) PC(34:3) PC(34:4) PC(34:5) PC(35:0) PC(35:1) PC(35:2) PC(35:3) PC(35:4) PC(35:5) PC(36:0) PC(36:1) PC(36:2) PC(36:3) PC(36:4) PC(36:5) PC(36:6) PC(37:0) PC(37:1) PC(37:2) PC(37:3) PC(37:4) PC(37:5 PC(37:6) PC(37:7) PC(38:0) PC(38:1) PC(38:2) PC(38:3) PC(38:4) PC(38:5) PC(38:6) PC(38:7) PC(39:0) PC(39:1) PC(39:2) PC(39:3) PC(39:4) PC(39:4) PC(39:5) PC(39:6) PC(39:7) PC(40:0) PC(40:1) PC(40:2) PC(40:3) PC(40:4) PC(40:5) PC(40:6) PC(40:7) PC(40:8)PC PC(40:9) PC(41:0) PC(41:1) PC(41:2) PC(41:3) PC(41:4) PC(41:5) PC(41:8) PC(42:0) PC(42:1) PC(42:2) PC(42:3) PC(42:40 PC(42:5) PC(42:6) PC(42:10) PC43:6) PC(44:1) PC(44:3( PC(44:5) PC(44:6) PC(44:7) PC(44:10) PC(44:12) PC(46:1) PC(46:2) PC-O(26:0) PC-O(26:1) PC-O(28:0) PC-O(28:1) PC-O(30:0) PC-O(30:1) PC-O(30:2) PC-O(31:1) PC-O(31:1) PC-O(31:3) PC-O(32:0) PC-O(32:1) PC-O(32:2) PC-O(32:3) PC-O(33:0) PC-O(33:1) PC-O(33:2) PC-O(33:3) PC-O(33:4) PC-O(33:4) PC-O(33:6) PC-O(34:0) PC-O(34:1) PC-O(34:2) PC-O(34:3) PC-O(34:4) PC-O(35:3) PC-O(35:4) PC-O(36:0) PC-O(36:1) PC-O(36:2) PC-O(36:3) PC-O(36:4) PC-O(36:5) PC-O(36:6) PC-O(36:7) PC-O(37:6) PC-O(37:7) PC-O(38:0) PC-O(38:1) PC-O(38:2) PC-O(38:3) PC-O(38:4) PC-O(38:5) PC-O(38:6) PC-O(40:0) PC-O(40:1) PC-O(40:2) PC-O(40:3) PC-O(40:4) PC-O(40:5) PC-O(40:6) PC-O(40:7) PC-O(40:8) PC-O(42:0) PC-O(42:1) PC-O(42:2) PC-O(42:3) PC-O(42:4) PC-O(42:5) PC-O(42:6) PC-O(44:3) PC-O(44:4) PC-O(44:5) PC-O(44:6), Sphingomyelin SM(30:1)  SM(31:0) SM(31:1) SM(32:1) SM(32:2) SM(33:1) SM(33:2) SM(34:1) SM(34:2) SM(35:1) SM(36:0) SM(36:1) SM(36:2) SM(37:1) SM(38:1) SM(38:2) SM(38:3) SM(39:1) SM(39:2) SM(40:1) SM(40:2) SM(40:4) SM(41:1) SM(41:2) SM(42:1) SM(42:2) SM(42:3) SM(43:1) SM(43:2) SM(44:1) SM(44:2), Ceramide Cer(34:0) Cer(34:1) Cer(34:1) Cer(38:1) Cer(40:1) Cer(41:1) Cer(42:1) Cer(42:2) Cer(43:1) Cer(44:0), Cholesteryl Esters CE(16:0) CE(16:1) CE(17:0) CE(17:1) CE(17:2) CE(18:1) CE(18:2) CE(18:3) CE(19:2) CE(19:3) CE(20:4) CE(20:5) CE(22:5) CE(22:6)

Species: Humans, Mice, Rats, Livestock

Validation or Publication:  Anal. Chem. 2019, 91, 22, 14407–14416; Aidin Foroutan, An Chi Guo, Rosa Vazquez-Fresno, Matthias Lipfert, Lun Zhang, Jiamin Zheng, Hasan Badran, Zachary Budinski, Rupasri Mandal, Burim N. Ametaj and David S. Wishart. The Chemical Composition of Cow’s Milk. J Agric Food Chem. 2019 May 1;67(17):4897-4914. PMID: 30994344

Additional information

Client Classification

Industry, Government, Academic