LC-MS Targeted (Biocrates p180)


LC-MS Targeted (Biocrates p180) metabolomic analysis is useful for plasma, serum urine, tissue, milk, CSF, meat, cell media, cell lysate, and cells.


Matrices / Biosamples:  Plasma, Serum, Urine, Tissue, Milk, CSF, Meat, Cell Media, Cell Lysate, Cells

Volume Requirement:  20 ul; 30-40 mg

Pathways: Amino acid metabolism, Fatty acid metabolism, Central carbon metabolism, Lipid metabolism, Urea Cycle. Redox Balance

Compound Classes:  Lipids, Fatty Acids, Amino Acids, Organic acids, Biogenic amines, Acylcarnitines, Phosphatidylcholines, LysoPCs, Sphingomyelins, Sugars, Neurotransmitters

Cost per Sample:  Academic/Government $115; Industry $160

Number of Compounds:  Up to 180

Quantitative:  Absolute

Compound List:  Carnitine, Acetylcarnitine, Propionylcarnitine, Propenoylcarnitine, Hydroxypropionylcarnitine, Butyrylcarnitine, Butenylcarnitine, Valerylcarnitine, Methylglutarylcarnitine, Hydroxyvalerylcarnitine (Methylmalonylcarnitine), Tiglylcarnitine, Glutaconylcarnitine, Hexenoylcarnitine, Pimelylcarnitine, Octanoylcarnitine, Nonaylcarnitine, Decanoylcarnitine, Decenoylcarnitine, Decadienylcarnitine, Dodecanoylcarnitine, Dodecenoylcarnitine, Tetradecanoylcarnitine (C14), Tetradecenoylcarnitine (C14:1) Hydroxytetradecenoylcarnitine, Tetradecadienylcarnitine, Hydroxytetradecadienylcarnitine, Hexadecanoylcarnitine, Hexadecadienylcarnitine, Octadecanoylcarnitine (C18), Octadecanoylcarnitine (C18:1), Octadecadienylcarnitine, lysoPhosphatidylcholine acyl C16:0 C17:0 C18:0 C18:1 C18:2 C20:3 C20:4 C26:0 C28:0 C28:1, Phosphatidylcholine diacyl C24:0 C26:0 C28:1 C30:0 C30:2 C32:1 C32:2 C32:3 C34:1 C34:2 C34:3 C34:4 C36:0 C36:1 C36:2 C36:3 C36:4 C36:5 C36:6 C38:0 C38:1 C38:3 C38:4 C38:5 C38:6 C40:1 C40:2 C40:3 C40:4 C40:5 C40:6 C42:0 C42:1 C42:2 C42:4 C42:6 C42:6, Phosphatidylcholine acly-alkyl C30:0 C30:1 C32:1 C32:2 C34:0 C34:1 C34:2 C34:3 C36:0 C36:1 C36:2 C36:4 C36:5 C38:0 C38:1 C38:3 C38:4 C38:5 C38:6 C40:1 C402 C40:3 C40:4 C40:5 C40:6 C42:0 C42:1 C42:3 C42:4 C42:5 C44:3 C44:4 C44:5 C44:6, Hydroxysphingomyeline C14:1 C16:1 C22:1 C22:2 C24:1, Sphingomyeline C16:0 C18:0 C18:1 C20:2 C22:3 C24:0 C24:1 C26:0 C26:1, Hexose

Species: Humans, Mice, Rats, Livestock

Validation or Publication: Chronic Kidney Allograft Damage;; Metabolomics 16, 59 (2020).; Human Urine Metabolome:; Zordoky BN, Sung MM, Ezekowitz J, Mandal R, Han B, Bjorndahl TC, et al. (2015) Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction. PLoS ONE 10(5): e0124844.

Additional information

Client Classification

Industry, Government, Academic