LC-MS (Targeted) for 1-Carbon Metabolism

Cost per Sample:  Academic/Government $40 CAD; Industry $52 CAD

Matrices / Biosamples:  Plasma, Serum, Urine, Tissue, Saliva, Milk, Cell Media, Cell Lysate, Cells

Volume Requirement:  20 uL; 30 mg

Species: Humans, Mice, Rats, Livestock

Pathways: 1-Carbon metabolism

Compound Classes:  Amino acids, vitamins, co-factors, lipid precursors

Number of Compounds:  10

Quantitative:  Absolute

Compound List:  Betaine, Folate, Homocysteine, L-Methionine, L-Serine, S-Adenosylmethionine, Tetrahydrofolate, Vitamin B12, Glutamate, Glycine

Validation or Publication: 

A Hassanzadeh Keshteli et al.  “Comparison of the metabolomic profiles of irritable bowel syndrome patients with ulcerative colitis patients and healthy controls: new insights into pathophysiology and potential biomarkers.”  Aliment Pharmacol Ther. 2019, 49, 723.

A Minerbi et al.  “Altered microbiome composition in individuals with fibromyalgia.”  Pain.  2019, 160, 2589.

J Zheng et al.  “Comprehensive Targeted Metabolomic Assay for Urine Analysis.”  Anal Chem.  2020, 92, 10627.

JB Magan et al.  “Impact of bovine diet on metabolomic profile of skim milk and whey protein ingredients.”  Metabolites. 2019, 9, 305.

A Foroutan et al.  “The Bovine Metabolome.”  Metabolites.  2020, 10, 233.

Note about Ordering:  Once you have added your choices to the cart and checked out, an email will be sent to you detailing your order. Next, we will contact you to clarify and confirm project details, upon which we will send you a statement of work, which will define the scope and total cost of your project and which will include further instructions, such as shipping of samples. Generally, after results and reporting, you will receive an invoice with payment instructions. For some projects, there may be a down payment. All prices are listed in Canadian dollars.

The Wishart Node of The Metabolomics Innovation Centre can accommodate almost any request for metabolomic analysis. If you don’t see what you are looking for in our shop, or would like assistance to design a budget-friendly project, please contact us and we would be happy to help.